Sincrotrón ALBA: una herramienta única para las empresas farmacéuticas
Sincrotrón ALBA: una herramienta única para las empresas farmacéuticas
Time: 1:00 pm - 1:30 pm
Date: 18/02/27
Synopsis
ALBA Synchrotron is a state-of-the-art facility that produces synchrotron light, enabling high-resolution visualization of the atomic structure of matter and in-depth analysis of its properties.
The different instruments available at ALBA are crucial in advancing drug discovery, efficacy assessment, and formulation development through the following approaches:
• Drug Discovery: X-ray crystallography enables precise visualization of macromolecular structures, such as antibodies and protein-drug complexes, at the atomic level. This detailed structural information significantly accelerates drug design and optimization, surpassing the capabilities of traditional methods.
• Drug Efficacy: Soft X-ray cryo-tomography provides a novel, complementary approach for studying the cellular architecture at medium resolution (50-60 nm). This technique offers very relevant information into the effects of drug compounds on cellular structures.
• Drug Development: synchrotron X-ray powder diffraction is a key tool for characterizing active pharmaceutical ingredient (API) formulations and providing information of crystallinity, polymorphism, with low detection limits and high peak resolution.
• Nanoparticle Characterization: Small-Angle X-ray Scattering is used to analyze the size, shape, and internal structure of nanoparticles, including drug delivery carriers, providing essential data for optimizing drug delivery systems.
ALBA is dedicated to scientific excellence and industrial innovation, supporting the advancement of drug research and development, contributing to societal well-being and progress.
SPEAKERS
Núria VallsIndustrial Liaison Scientist - ALBA Synchrotron
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